Modulating aging and longevity /
"After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologists are now in a position to construct general principles of ageing and explore various possibilities of intervention using rational approaches....
Saved in:
| Andre forfattere: | |
|---|---|
| Format: | Bog |
| Sprog: | English |
| Udgivet: |
Dordrecht ; Boston :
Kluwer Academic Publishers,
c2003.
|
| Serier: | Biology of aging and its modulation ;
v. 5 |
| Fag: | |
| Online adgang: | Table of contents only Publisher description |
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| 245 | 0 | 0 | |a Modulating aging and longevity / |c edited by Suresh I.S. Rattan. |
| 260 | |a Dordrecht ; |a Boston : |b Kluwer Academic Publishers, |c c2003. | ||
| 300 | |a vi, 333 p. : |b ill. ; |c 25 cm. | ||
| 490 | 1 | |a Biology of aging and its modulation ; |v v. 5 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Editorial : about the series "Biology of aging and its modulation" / S. Rattan -- Ch. 1. Modulating aging, longevity determination and the diseases of old age / L. Hayflick -- Ch. 2. The modulation of lifespan by natural selection / R. Holliday -- Ch. 3. Early-life factors modulating lifespan / L. A. Gavrilov and N. S. Gavrilova -- Ch. 4. Selective breeding for slower aging and greater lifespan / L. S. Luckinbill -- Ch. 5. Slowing down cellular aging in vitro / I. P. Trougakos, N. Chondrogianni, A. Pimenidou, M. Katsiki, C. Tzavelas and E. S. Gonos -- Ch. 6. Escaping cellular senescence in vitro / R. Wadhwa, P. Polly, A. Nagpal and S. C. Kaul -- Ch. 7. Stress, cells and tissue aging / J.-F. Dierick, C. Frippiat, M. Salmon, F. Chainiaux and O. Toussaint -- Ch. 8. Hormesis in aging and longevity / N. Minois and S. I. S. Rattan -- Ch. 9. Therapeutic interventions for age-related muscle wasting / T. Shavlakadze and M. D. Grounds -- Ch. 10. Slowing down aging in the skin / G. S. Ashcroft and J. J. Ashworth -- Ch. 11. Antioxidants as modulators / E. Le Bourg -- Ch. 12. Mitochondrial interventions in aging and longevity / C. Driver -- Ch. 13. Hormonal interventions of aging and longevity / M. K. Thakur -- Ch. 14. Effect of melatonin on longevity / V. N. Anisimov -- Ch. 15. Nutritional modulation of aging : effect of caloric restriction / M. A. Pahlavani, M. L. Hamilton and A. Richardson -- Ch. 16. Small peptide-associated modulation of aging and longevity / V. N. Anisimov and V. Kh. Khavinson -- Ch. 17. Gene expression profiling to study aging and its modulation / S. Welle. | |
| 520 | 1 | |a "After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologists are now in a position to construct general principles of ageing and explore various possibilities of intervention using rational approaches. While not giving serious consideration to the claims made by charlatans, it cannot be ignored that several researchers are making genuine attempts to test and develop various means of intervention for the prevention and treatment of age-related diseases, for regaining the functional abilities and for prolonging the lifespan of experimental organisms. This provides the most up-to-date information and a critical evaluation of a variety of approaches being tried for modulating aging and longevity, including dietary supplementation with antioxidants, vitamins and hormones, genetic engineering, life-style alterations, and hormesis through mild stress. The goal of research on ageing is not to increase human longevity regardless of the consequences, but to increase active longevity free from disability and functional dependence. The book will be most useful for researchers, healthcare persons, cosmetologists, and pharmaceutical industry."--BOOK JACKET. | |
| 650 | 0 | |a Aging |x Molecular aspects. | |
| 650 | 0 | |a Longevity. | |
| 650 | 1 | 2 | |a Aging |x physiology. |
| 650 | 2 | 2 | |a Cell Aging |x physiology. |
| 650 | 2 | 2 | |a Longevity |x physiology. |
| 700 | 1 | |a Rattan, Suresh I. S. | |
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| 830 | 0 | |a Biology of aging and its modulation ; |v v. 5 | |
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