Applications of pharmacokinetic principles in drug development /
Tallennettuna:
| Muut tekijät: | |
|---|---|
| Aineistotyyppi: | E-kirja |
| Kieli: | English |
| Julkaistu: |
New York ; London :
Kluwer Academic/Plenum,
c2004.
|
| Sarja: | Springer Nature Book Archives Millennium (2000-2004)
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| Aiheet: |
Sisällysluettelo:
- Machine derived contents note: Efficient and Effective Drug Development
- Wayne A. Colburn and Gene Heath
- Bioanalytical Methods: Challenges and Opportunities In Drug Development 21
- Mark L. Powell and Steve E. Unger
- Predicting Human Oral Bioavailability using In Silico Models 53
- Lawrence X. Yu, Christopher D. Ellison, and Ajaz S. Hussain
- Drug Metabolism in Preclinical Development 75
- Michael W. Sinz
- Interspecies Scaling 133
- Thierry Lave, Olivier Luttringer, Patrick Poulin, and Neil Parrott
- Human Drug Absorption Studies in Early Development 177
- David V. Prior, Alyson L. Connor, and Ian R. Wilding
- Food-Drug Interactions: Drug Development Considerations 195
- David Fleisher and Laurie Reynolds
- Global Regulatory and Biopharmaceutics Strategies in New Drug
- Developm ent: Biowaivers 225
- Elora Gupta and Elizabeth Yamashita
- Special Population Studies in Clinical Development: Pharmacokinetic
- Considerations 245
- John M. Kovarik
- Drug-Drug Interactions 307
- Shiew-Mei Huang
- Pharmacokinetic/Pharmacodynamic Modeling in Drug Development 333
- Shashank Rohatagi, Nancy E. Martin, and Jeffrey S. Barrett
- Population Pharmacokinetic and Pharmacodynamic Modeling 373
- Roger Jelliffe, Alan Schumitzky, Aida Bustad, Michael Van Guilder,
- Xin Wang, and Robert Leary
- Role of Preclinical Metabolism and Pharmacokinetics in the Development of
- C elecoxib 405
- Susan K. Paulson and Timothy J. Maziasz
- The Role of Clinical Pharmacology and of Pharmacokinetics in the
- Development of Alendronate - A Bone Resorption Inhibitor 427
- Arturo G. Porras and Barry J. Gertz
- Optimizing Individualized Dosage Regimens of Potentially Toxic Drugs 477
- Roger W. Jelliffe, Alan Schumitzky, Robert Leary, Andreas Botnen,
- Ashutosh Gandhi, Pascal Maire, Xavier Barbaut, Nathalie Bleyzac, and
- Irina Bondareva
- Appendix 529
- Index 545.